A new profile of activation for macrophages during obesity

Not available in english.

[1] Kratz et al. Metabolic disfunction drives a mechanistically distinct proinflammatory phenotype in adipose tissue macrophages. Cell Metab., 2014.

[2] Weisberg SP et al. Obesity is associated with macrophage accumulation in adipose tissue. J. Clin. Invest., 2003.

[3] Xu H. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J. Clin. Invest., 2003.

[4] Murray PJ et al. Macrophage activation and polarization: nomenclature and experimental guidelines. Immunity, 2014.

Bruno Chaussê de Freitas
Biólogo (UFPB), Doutorado em Ciências Biológicas (USP), pós-doutorando na Faculdade de Ciências Médicas da Unicamp. Vinculado ao Centro de Pesquisa em Obesidade e Comorbidades, atua na área de bioenergética, metabolismo e obesidade.